Pyrrole Disorder

Pyrrole Disorder Symptoms

 

Moody. That’s the word loved ones, friends, and co-workers usually use to describe the person in their life suffering from untreated pyrrole disorder. Everyone walks on eggshells whenever this person is around.

No one ever knows what’s going to set them off. Like a time bomb ticking away, stress continually builds inside the pyroluric’s body until a full-blown eruption occurs. Then the damage is done. Bridges are burned, feelings hurt, and grudges formed.

It’s not uncommon to see patterns of relationship issues with pyroluric patients, both adult and adolescent.

What is Pyrrole Disorder? It is a little known condition which can be initiated from severe or chronic stress or emotional trauma, which then triggers a genetic predisposition for excess production of a compound called HPL, which causes nutrient deficiencies. Because food nutrients are needed for a lot of functions and processes in your body, a deficiency in more than one nutrient will cause many seemingly separate symptoms. Specific nutrient deficiencies cause symptoms which result in Pyrrole Disorder (PD).

Many GPs and doctors don’t know about or recognise PD, as it just looks like you have a bunch of fairly common symptoms, including:

  • headaches and migraines
  • digestive complaints – constipation, reflux, bloating
  • poor tolerance to stress
  • depression and/or anxiety
  • sleep issues (can’t get to sleep, or interrupted sleep)
  • poor immune system and lots of infections
  • allergies and intolerances to foods or environmental substances
  • sensitivity to light, sounds, tastes
  • and many more symptoms (as shown in the above picture).

You don’t need to have all these symptoms, but having more increases the likelihood. When I see some or all of these symptoms together as I do in many clients, I look for the root causes for them all. I also use a screening questionnaire, analysis of pathology results, and specific pyrrole tests.

Pyrroles is nothing to be worried about! If anything it is great to have this diagnosis, as it is very easily treatable mainly with nutritional medicine! I’ve seen the condition in children as well as adults over 60 years of age, and it’s always a relief to finally have an answer to their health issues!

Pyrroles causes nutritional deficiencies mainly in zinc and vitamin B6, but also of lesser deficiencies in other B-vitamins, magnesium, omega-6 fats and others. Multiple deficiencies lead to all of the symptoms above, and more.

Pyrroles is very frequently seen running in families across multiple generations. It is VERY common in those with Irish and Celtic family history, and the reasons for this are unknown.

Some research shows that PD itself is very commonly linked to, and probably even a cause of bipolar disorder, schizophrenia, some autism disorders and other neurological and behavioural conditions.

If you recognise many of the above symptoms (in the picture) in yourself, your children, or other people you know, it would be a good idea to see if Pyrroles may be the cause! I have seen substantial reductions of symptoms with the nutritional medicine treatment for this condition! And those who have improved feel like they have their life (and health) back again!

Pyroluria is a an oxidative stress induced physiological disorder.
Pyrroles needed for the formation of the porfirin ring of the heme are excessively excreted.
This leads to a depletion of the body of vitamin B6 and Zinc.

In normal urine, the amount of pyrroles excreted is small, less than 20 ug/dL.

It has been reported that kryptopyrrole will form a Shiff base with the aldehyde form of vitamin B6 in the blood.

This combination will then bind with zinc. As large amounts of kryptopyrroles are excreted in the urine, zinc and b6 will be depleted.

PyrroleDisorder

 

References.

https://www.integrativepsychiatry.net/pyroluria.html

http://www.biobalance.org.au/articles/100

http://www.news.com.au/tablet/could-you-have-pyrrole-disorder/news-story/13971de5444b75d924a7c9b75f29928a

http://www.safelabs.com.au/urinary_kryptopyrrole_testing.php

https://www.todaytonightadelaide.com.au/stories/pyrrole-disease

https://walsh.med.harvard.edu/pubs/PDFs_2/Pyrroles_review.pdf

https://www.ncbi.nlm.nih.gov/pubmed/18383989

www.biobalance.org.au/_downloads/discerning-the-mauve-factor-part-ii-galley.pdf

www.lifescienceglobal.com/pms/index.php/jnt/article/download/2923/pdf_7

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342893/

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