Memory loss
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Memory Nutrients

Natural Products that help with retaining your memory

MAO–B inhibitors can help your nerve cells make better use of the dopamine that they have. Monoamine oxidase type B is an enzyme that wrongly hooves up dopamine that is not being used by your brain. MAO-B inhibitors stop this enzyme so that more dopamine becomes available to treat your symptoms.

Natural Products Screening for the Identification of Selective Monoamine Oxidase-B Inhibitors:

1. Gan Cao (Glycyrrhiza Uralensis Root)

MAO-B Inhibition Very High (IC50 <.07 mg/ml)

Gan Cao is a type of licorice (same genus), and is used in much the same way. Its traditional uses involves female disorders, digestive disorders, ulcers, and heart arrythmias. One of the most interesting sue of this plant, is as a “harmonizer” of other medicinal plants.

In Chinese traditional medicine this is one of the main herbs used in formulas for its ability to improve the outcomes of other plants.

The roots of Glycyrrhiza uralensis (aka Chinese licorice; family Leguminosae) is another commonly used medicinal plant in traditional Chinese and natural medicine. Our new finding that GUREE inhibits hMAO-B selectively is supported by our previous finding for its hMAO-B inhibition [].

Interestingly, GUR was more selective than Glycyrrhiza glabra in our screen. Reported Glycyrrhiza uralensis different active constituents from other Glycyrrhiza genuses may influence its MAO-B selective inhibition []. GUR contains unique phytochemicals including isoprenylated phenolics [] flavonoids, chalcones, and triterpene saponins [].

Chalcone isoliquiritigenin, is an inhibitor for MAO-B [] with multifunctional anti-inflammatory, antioxidant, cytoprotective [] cellular detoxification system activator [] and anti-apoptotic [] anti-amyloid-β toxicity [] neuroprotective properties. GUR total flavonoid extracts showed neurogenesis protective effect in depressed rats model [].

The flavonoid liquiritin showed antioxidant and antiapoptotic neuroprotective effects in mice [] and ameliorated depression in rat model []. Its benzopyran dehydroglyasperin-C also showed neuroprotection []. Xiao Yao San, a traditional herb combination containing GUR for chronic depression, was effective in both animal models and clinical trials [,].

Other multifunctional properties of GUR constituents included reducing pro-inflammatory cytokines, nitric oxide, reactive oxygen species, lipid peroxidation [], and mitochondrial impairment []. Interestingly, GUREE reports covered its chemopreventive [] and anti-diabetic properties []. Therefore, specifically investigating GUREE as a selective MAO-BI could be beneficial.

2. Psoralea Fruit Babchi (Psoralea Corylifolia)

MAO-B Inhibition Very High (IC50 <.07 mg/ml)

Psoralea fruit is a lesser known Ayurvedic and Traditional Chinese medicinal plant species. It was used in the past for conditions like vitiligo and other skin related conditions. Recently it has received a lot of attention for its MAO inhibiting properties, and is suggested to be a norepinephrine, re-uptake inhibitor.

In addition, the seeds of Psoralea corylifolia (aka, Bu Gu Zhi or Babchi; family Leguminosae) are important in traditional Chinese and Ayurvedic medicines []. PCSEE was one of the most potent and selective hMAO-BI using our fluorometric screening assay.

Our PCS findings are supported by our previous investigations on its hMAO-B inhibitory potency tested spectrophotometrically [], and its selectivity for hMAO-B using a luminescence assay [].

Previous PCS screened extracts for active constituents revealed that the ethanolic extract composes more medically active compounds than some other PCS extracts, which makes it a better candidate for novel phytomedicines [].

PSCEE is rich in benzopyrone structure constituents including coumarins and flavonoids. PCS furocoumarins psoralen and isopsoralen showed rat MAOs activities inhibitions [], which were supported by total furocoumarins potent antidepressant effects on mice []. PCS also contains isoflavones, which have been used as dietary supplements in various diseases, including osteoporosis, cognitive dysfunction, cardiovascular disease, and inflammation [], which are close to PCS multifaceted properties [].

We previously investigated bavachinin and genistein flavonoids constituents of PCS. Bavachinin exhibited a selective hMAO-B inhibition [] while isoflavone genistein was similarly potent but less selective against hMAO-B [].

Moreover, PCSEE contains monoterpenes that protected against the MAO-B substrate 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) SN cell damage and MPTP-induced motor deficits in PD model [], inhibited DA and norepinephrine (NE) transporters [], and showed antidepressant effects with catecholamine neurotransmitters regulation [,].

The PCS extracts were also neuroprotective against the MPTP precursor MPP+ [] and the nitropropionic acid (3-NP) induced cytotoxicity and mitochondrial dysfunction [].

Although the seeds are used in dermatological disorders health supplements [] and increasingly investigated on in vitro and animal models, the extract and its phytochemicals clinical effects on degenerative diseases are yet to be clinically considered.

From our results, the observed association between PCS constituents MAO-B inhibitions and the extracts neuroprotection in the previous reports suggests more investigations for potential beneficial PCS phytochemicals for PD.

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3. Ferula assafoetida roots

MAO-B Inhibition Very High (IC50 <0.07 mg/ml)

This resin has been used as a spice and a phytomedicine around the globe for centuries. In the folklore medicine, it is mostly used in asthma, gastrointestinal disorders, and neuronal disorders [].

In recent reports, the resin improved memory and learning in rats [], and exhibited neuroprotection and nerve stimulation in mice peripheral neuropathy [], and anticonvulsant properties [].

FAR contains bioactive phytochemicals such as polysulfides, sesquiterpenes, sesquiterpene-coumarins, diterpenes, phenolics, and flavonoids [,]. Its coumarin umbelliprenin showed anti-inflammatory properties [], while ferulic acid showed anti-atherosclerotic, antioxidant, and neuroprotective properties [] and became a candidate for AD [].

Therefore, investigations on the resin concerning PD need to be considered.

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4. Amur Cork Tree (Phellodendron Amurense)

MAO-B Inhibition Very High (IC50 <.07 mg/ml)

Amur cork tree is one of the 50 fundamental Chinese herbs. It’s commonly used for it’s sedative, muscle relaxant, antiarrhythmic, positive inotropic, hypotensive, and antibacterial actions.

 Phellodendron amurense (aka Amur cork tree; family Rutaceae) is a meagerly investigated Chinese medicinal plant. In our study, its bark ethanolic extract clearly was a selective hMAO-BI as its potent inhibition was previously spectrophotometrically confirmed [].

The plant constituted alkaloids such as phellodendron, palmatine, jatrorrhizine, and berberine [,] where the later displayed safe antidepressant-like activities in mice by the possible mechanism MAO-A inhibition and increasing DA, NE and serotonin brain levels [,].

PAB is high in the flavone tetramethyl-o-scutellarin, and the triterpenoids limonoids []. Limonoid obacunone was found neuroprotective in glutamate-induced neurotoxicity in vitro [].

In clinical studies, PAB extract supplement safely reduced cortisol [], and relieved mild anxiety in women []. Also, PAB inhibited pro-inflammatory cytokines [,] and protected from prostate tumors progression [], property found in some MAO-AIs [].

Based on our results and literature, there is a lack of knowledge on MAO-B inhibition and selectivity benefits of PAB extracts and phytochemicals. Further studies on PABEE as MAO-BI source for PD are highly recommended.

Natural Products Screening for the Identification of Selective Monoamine Oxidase-B Inhibitors

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898948/

 

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The-Role-of-Exercise-in-Reducing-Inflammation-and-Promoting-Joint-Health

The Role of Exercise in Reducing Inflammation and Promoting Joint Health

Introduction

Exercise is often hailed as a valuable asset for maintaining, generally speaking, health and
prosperity. While it&#39;s typically connected with weight the board and cardiovascular wellness,
its advantages expand well past these perspectives. One of the less popular yet urgent
benefits of customary exercise is its role in reducing inflammation and promoting joint
health. In this article, we will investigate how exercise can significantly keep your joints
healthy and even improve conditions like facet joint infection.

Understanding Inflammation and Joint Health

Inflammation is the body’s regular reaction to injury or infection. A defensive instrument
helps the body recuperate and fend off microorganisms. In any case, ongoing inflammation
can prompt various health issues, including joint problems. Conditions like osteoarthritis and rheumatoid joint pain are described by constant joint inflammation, resulting in pain,
firmness, and diminished versatility.

Facet Joint Infection: A Special Test

Facet joints are little synovial joints situated along the spine that assume a critical part in
spinal steadiness and portability. While facet joint infections are generally intriguing,
contrasted with other joint diseases, they can be particularly challenging because of their
area and expected influence on spinal health. Facet joint infection is brought about by
microorganisms infiltrating the facet joints, leading to inflammation and pain in the back
and neck. In some cases, medical professionals may recommend a treatment known as facet
joint injection to address issues related to these joints. Facet joint injections involve the
precise administration of medication or a therapeutic substance directly into the affected
facet joint.

The Association Among Exercise and Joint Health

Customary exercise offers many advantages for joint health, fundamentally by addressing
inflammation and supporting, generally speaking, joint capability. This is the way exercise
can decidedly affect joint health, including its possible role in managing conditions like facet
joint infection:

1. Weight The board

Carrying an overabundance of body weight puts extra weight on the joints, particularly
those in the lower body. This can add to the turn of events or compounding of joint issues
like osteoarthritis. Exercise supports the board&#39;s weight, helping to diminish the heap on the
joints and decline the gamble of joint-related problems.

2. Worked on Joint Oil

Exercise advances the creation of synovial liquid, a characteristic grease for joints. This
assists with maintaining joint portability and lessens rubbing, which can mitigate uneasiness
related to conditions like osteoarthritis.

3. Strengthening Muscles Around Joints

Solid muscles go about as defensive help structures for joints. Ordinary exercise, including
strength training, can help fabricate and maintain bulk, providing added joint steadiness.
Strengthening the muscles around the spine can be especially useful for facet joint health.

4. Upgraded Blood Flow

Exercise further develops blood course all through the body, including the joints. This
improved flow conveys fundamental supplements to the joints and eliminates side effects,
aiding in the maintenance and maintenance of joint tissues.

5. Reducing Inflammation

Exercise has been displayed to affect the body. It can assist with regulating the safe
framework, reducing the development of support of inflammatory particles. This can be
particularly applicable in managing persistent inflammation related to rheumatoid joint pain
and facet joint infection.

6. Upgraded Scope of Movement

Customary active work, including stretching and adaptability exercises, can work on the
joint scope of movement. This is vital for maintaining joint health and preventing solidness,
which can be a typical complaint among individuals with joint issues.

Choosing the Right Exercises

With regards to promoting joint health and managing inflammation, not all exercises are
made equivalent. Low-influence exercises are often the most secure and best decision for
individuals with joint issues, including those with facet joint infection. Here are some
appropriate exercise choices:

1. Swimming: Swimming is a brilliant low-influence exercise that supports joint health.
The lightness of water diminishes weight on the joints while providing a full-body exercise.

2. Cycling: Cycling is a joint-accommodating, oxygen-consuming exercise that strengthens
leg muscles without putting unreasonable strain on the joints.

3. Yoga: Yoga offers delicate stretching and adaptability exercises that can work on joint
portability and diminish solidness. It likewise advances unwinding, which can be
advantageous for managing pressure-related inflammation.

4. Judo: Yoga is a low-influence military craftsmanship that underscores slow, controlled
developments. It can further develop balance, joint strength, and, by and large portability.

5. Strength Training: Strength training with legitimate structure and strategy can assist
with building bulk, providing backing and soundness to the joints. It&#39;s crucial to start with
light loads and progress continuously.

Consulting a Healthcare Professional

Before beginning any exercise program, particularly if you have joint issues or conditions like
facet joint infection, it&#39;s significant to talk with a healthcare professional. They can give
customized proposals and guarantee that your picked exercise routine is protected and
proper for your particular requirements.

Conclusion

Exercise is a powerful device for reducing inflammation and promoting joint health.
Whether you are aiming to forestall joint issues, oversee ongoing circumstances like
osteoarthritis or rheumatoid joint inflammation, or address special difficulties like facet joint
infection, everyday actual work can play a critical part in maintaining your joint health. By
choosing the right exercises and seeking direction from healthcare professionals, you can
leave on an excursion to more grounded, healthier joints and better general personal.

Facet joint injections

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Attitude Is Key

 

With everything going on in the world nowadays, it can be hard to keep a positive mindset. 

Overcoming negative thoughts and trying to stay consistent in the way we feel and act can be hard. 

If you can learn to keep a positive mental attitude through all the hard things that come with life, you are setting yourself up for success in many different ways.

Before being able to start thinking positive, you need to be able to practice mindfulness. 

This includes self-care and meditating. 

Once you know how to focus more on your inner self and how to calm your mind, you will find that thinking positive is much easier and you can overcome your negative thoughts. 

You can then start incorporating mindfulness and gratitude in your every day life. 

This guide that will give you guidance on how you can easily be more positive and change your mental outlook on life.

Here is what you’ll learn:

  • The routines and habits you need to start forming today to change your mental outlook on life; 
  • How creating positivity in your life can change how you live completely; 
  • Why you need to focus on your attitude to meet your goals; 
  • How to focus on yourself and your habits to push out negativity;  
  • How to find the best way to show gratitude and appreciate every single day; 
  • How to start positively self talking to yourself to ensure your attitude is the best it can be; 
  • How to practice mindfulness and self care to help put you in the right mindset; 
  • How to improve your attitude even when you think times are tough; 
  • Ways to strengthen your relationships with others who are also positive; 
  • Rules for staying away from those that are negative and do not support your positive mindset;  
  • Successful techniques for breaking old negative habits that can bring you down; 
  • How you can practice being mindful and open to life;  
  • Customized activities to center your thoughts on positivity and appreciation; 
  • Practical ways to be maintain a positive mental attitude in daily life;  
  • Numerous techniques to be more open and positive; 
  • Over 20 additional resources that will help you with mastering the art of positivity; 
  • And so much more!
Attitude is Key
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Time Mastery

In our society, we often feel the need to be busy all the time, even when there is nothing urgent or important to get done. 

If you are constantly busy but feel like you are not really accomplishing anything, it’s time to make a change. 

Even when you feel like you don’t have free time, there are simple steps you can take to stop being busy without a purpose.

Getting things done is a part of time management. If you plan to be productive and accomplish your goals, you need to get your time under control. 

Setting schedules and routines is only part of the way to control your time. 

There are also techniques and tricks you need to know about so that you can manage your time without being stressed.

This ebook will give you guidance on how you can easily achieve your goals and learn to master your time.

Here is what you’ll learn:

  • The routines and habits you need to start forming today to stop being busy and start being productive; 
  • How achieving your goals gives you a purpose; 
  • Why you need to focus on schedules and routines to get the most out of life; 
  • How to focus on yourself and your habits to push out procrastination;  
  • How to find the perfect way to master the art of keeping time; 
  • How to create a schedule to learn time management techniques so you can get more things done; 
  • How to use time management to improve your business and relationships with others; 
  • How to improve your self-control and transform it into productivity; 
  • Ways to strengthen your relationship with yourself so you move towards goal achievement; 
  • Rules for staying away from those that do not support your journey into becoming a new person;  
  • Successful techniques for breaking old habits of procrastination; 
  • How you can practice time management and the Pomodoro technique;  
  • Customized ideas to master time and set goals; 
  • Practical ways to maintain your goals and achievements;  
  • Numerous techniques to be more open about time management; 
  • Over 20 additional resources that will help you with mastering your time; 
  • And so much more!

 

Time Mastery
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How Essential Oils Can Enhance Your Stress Meditation Practice?

 

Introduction 

 

Stress can take a toll on the mind and body, making it crucial to find effective ways to manage it. One such method is meditation, which has been shown to reduce stress levels positively. However, incorporating essential oils into your meditation routine can take your stress support practice to the next level.  

 

With their unique therapeutic properties, essential oils can help promote relaxation, calm the mind, and reduce stress. In this article, we’ll explore how essential oils can enhance your stress meditation practice and provide tips on choosing suitable oils for your needs. 

 

1. The Science Behind Essential Oils and Their Effect on the Brain 

 

Essential oils have a powerful effect on the brain. When inhaled, the aroma of essential oils stimulates the olfactory system, which is responsible for processing smells. The olfactory system is connected to the limbic system, which controls emotions, mood, and memory. 

 

When inhaled, essential oils can trigger a response in the limbic system, leading to a sense of relaxation and calm. It is why aromatherapy often uses essential oils to promote peace and reduce stress. 

 

2. Choosing the Right Essential Oils for Your Stress Meditation Practice 

 

When choosing essential oils for stress meditation, it’s necessary to consider their properties and how they can benefit you.  

 

Some essential oils are energizing and can promote focus, while others are more calming and help you relax. 

 

Lavender is a popular choice for stress meditation as it is known for its relaxing and calming properties.  

 

Peppermint and eucalyptus are energizing and can help promote focus and concentration.  

 

Frankincense is also famous as it is known for its grounding and centering properties. 

 

3. How to Incorporate Essential Oils into Your Meditation Routine 

 

Incorporating essential oils into your meditation routine is a simple yet effective way to enhance your practice and relieve stress. Here are some tips for seamlessly integrating essential oils into your meditation routine: 

 

  • Choose the suitable oils: Select oils that promote relaxation, calm the mind, and reduce stress levels, such as lavender, bergamot, and frankincense.

 

  • Diffuse or apply topically: Use a diffuser to fill the room with the scent of your chosen oil, or apply it topically to the wrists, temples, or neck.

 

  • Set the mood: Dim the lights, light candles, and play calming music to create a serene environment for your meditation practice.

 

  • Take deep breaths: Inhale the aroma deeply, focusing on the scent and sensation of the oil in your body.

 

4. Best Essential Oils for Stress Relief and Relaxation 

 

In addition to lavender, several other essential oils are known for their stress-relieving and relaxing properties. These include: 

 

  • Bergamot: Bergamot oil has a fresh and citrusy scent that can help reduce stress and anxiety. It can also boost mood and energy levels.

 

  • Chamomile: Chamomile oil is a natural sedative that promotes relaxation and improves sleep quality. It also has anti-inflammatory and digestive benefits.

 

  • Clary Sage: Clary sage oil is known for its calming properties and can help reduce anxiety and stress. It’s also believed to regulate hormones and relieve menstrual cramps.

 

  • Ylang-Ylang: Ylang-ylang oil has a sweet floral aroma that can help reduce tension and promote relaxation. It’s often used in aromatherapy to ease anxiety and depression.

 

5. The Role of Aromatherapy in Enhancing Your Meditation Experience 

 

Aromatherapy is the practice of using essential oils to promote well-being and balance. When used with meditation, aromatherapy can enhance your experience by promoting relaxation, reducing stress, and helping you achieve a deeper state of meditation. 

 

6. Precautions and Safety Measures When Using Essential Oils for Meditation 

 

While essential oils are generally safe, taking precautions for meditation is necessary. 

 

Always dilute essential oils with a carrier oil before applying them to your skin, and avoid using them near your eyes or mucous membranes. 

 

It’s also essential to use high-quality essential oils and to avoid synthetic fragrances, which can contain harmful chemicals. 

 

7. The Synergy of Essential Oils and Meditation for Overall Well-Being 

 

When used together, essential oils and meditation can promote overall well-being. Meditation can help reduce stress, while essential oils can enhance the meditative experience by promoting relaxation and reducing anxiety. 

 

8. Tips for Creating a Soothing and Relaxing Meditation Space with Essential Oils 

 

Creating a soothing and relaxing meditation space is critical to achieving a deeper state of relaxation during your practice. Here are some tips for creating a calming meditation space with essential oils: 

 

  • Choose a quiet space: Find a quiet and peaceful space where you won’t be disturbed during your meditation practice. It could be a spare room, a corner of your bedroom, or even outside in nature.

 

  • Set the mood with essential oils: Use a diffuser or apply essential oils topically to create a calming and relaxing atmosphere. Some of the best essential oils for promoting relaxation and reducing stress include lavender, bergamot, and chamomile.

 

  • Use calming colors: Choose calming colors such as blue, green, or neutral tones for your meditation space. These colors can help promote a sense of calm and relaxation.

 

  • Incorporate natural elements: Bringing in natural ingredients such as plants or a water feature can help create a peaceful and calming atmosphere.

 

  • Use comfortable seating: Use comfortable seating, such as a meditation cushion or chair, to help you relax during practice.

 

9. Frequently Asked Questions about Essential Oils and Meditation 

 

Can essential oils be harmful during meditation? 

While essential oils are generally safe, taking precautions for meditation is necessary. Always dilute essential oils with a carrier oil before applying them to your skin, and avoid using them near your eyes or mucous membranes. 

 

Can essential oils help with anxiety during meditation? 

Yes, essential oils can be beneficial in reducing stress during meditation. Essential oils such as lavender, chamomile, and bergamot are known for their calming properties and can help promote relaxation. 

 

What is the best way to use essential oils during meditation? 

There are several ways to use essential oils during meditation, including using a diffuser or applying them topically. Choosing high-quality essential oils and diluting them with a carrier oil is vital before applying them to your skin. 

 

How often should I use essential oils during meditation? 

The frequency of using essential oils during meditation is a personal preference. Some people use them every time they meditate, while others use them only when they need extra relaxation or stress relief. 

 

Conclusion 

 

Incorporating essential oils into meditation can be a game-changer for reducing stress and promoting relaxation. With suitable essential oils and calming meditation space, you can take your practice to the next level and experience the full benefits of meditation. Remember to take precautions when using essential oils, and always choose high-quality oils for the best results. 

How Essential Oils Can Enhance Your Stress Meditation Practice

https://www.aurleaf.com/c/product-category/stress-relief/

Learn Google Meet
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Google Meet Mastery

 

Google Meet Mastery is a new powerful report that explains how people can get the best results from the Google Meet video conferencing platform. Readers of the report will learn the most important features of Google Meet and how they can use these to their advantage.

Readers will learn what they can do with Google Meet and how they can use the video conferencing platform on any device. They will discover how easy it is to get started with Google Meet and learn about the features of the free Google Meet account. The report reveals the basic features of Google Meet and how the reader can master them quickly.

The reader will also learn about setting up and joining meetings in Google Meet. It is essential that the reader fully understands how meetings work and how they can initiate them or join meetings that have been set up by others. It will be easy for the reader to master the meeting features of Google Meet once they have read the special report.

When the reader creates a new meeting using Google Meet, they need to understand the process for adding people to this meeting. The report describes this in detail and takes the reader through a simple step-by-7-step process. Readers will also discover how they can remove someone from a meeting.

The use of closed captions is another feature of Google Meet and readers will learn how to turn this on and off. They will also learn about other useful Google Meet features such as muting their microphone, pinning participants, using chat, and changing the background. This is a must have report for those that want to master Google Meet.

Google Meet Mastery